Treatment
Morton’s neuroma surgery: options, recovery and results
Neurectomy or nerve release for Morton’s neuroma: when surgery is considered, what recovery involves, and what studies show.
Medically reviewed by Dr. Efe Ozturk · Last reviewed
When surgery is considered
Most people with Morton’s neuroma start with simple steps: roomy shoes, padding, orthotics, activity changes and, in selected cases, an injection.[1] Surgery enters the conversation when pain persists despite a well-tried course of these measures, interferes with daily life, and the diagnosis is well supported. In a review of people treated with corticosteroid injections, nearly 30% eventually had surgery because of persistent pain.[4] For the full stepwise approach, see Morton’s neuroma treatment, and for the condition itself, Morton’s neuroma.
The two main operations
Neurectomy (removing the nerve segment)
The surgeon removes the thickened part of the nerve between the toes. It can be done through an incision on the top of the foot (dorsal approach) or on the sole (plantar approach). Because the nerve that supplied feeling to the adjoining sides of two toes is removed, some numbness there is expected and is usually permanent.[5]
The two approaches have different trade-offs:
- In a pooled analysis, scar tenderness was more common after the plantar approach (about 17%) than after the dorsal approach (about 6%). Reoperation and overall complication rates were not significantly different.[6]
- In a single-center comparison of 37 people, satisfaction and function scores did not differ between the two approaches.[7] A randomized trial included in a 2024 Cochrane review also found similar satisfaction, although the certainty of that evidence is low.[8]
Neurolysis or decompression (releasing the nerve)
In this approach the surgeon divides the ligament that lies over the nerve between the metatarsal bones, and sometimes moves the nerve out of the way, without removing it. The aim is to relieve pressure while keeping the nerve’s feeling. A review of operations other than neurectomy found that after neurolysis, fewer people had ongoing nerve symptoms than after neurectomy. It also noted that minimally invasive decompression techniques had less reliable results, and that high-quality studies were limited, so it remains unclear whether these operations are better than neurectomy.[2]
A small case series of 12 people who had the ligament released alone reported a drop in average pain scores from about 6.4 to 2 out of 10 after about a year, with no recurrent neuroma or lasting numbness. It is encouraging but short-term and small.[9]
What studies show about results
A meta-analysis of 35 studies including 2,998 people compared three treatments:
| Outcome | Injection | Neurolysis | Neurectomy |
|---|---|---|---|
| Complete pain relief | 43% | 68% | 74% |
| Complete satisfaction | 35% | 63% | 57% |
| Needed further surgery | 15% | 2% | 5% |
The authors found that complication rates did not differ between the treatments, and that surgery, by either method, trended toward more complete pain relief than injection.[3] These figures pool many studies of different designs and quality, and the people treated with each method were not necessarily the same. They show a general pattern, not what will happen to you.
Recovery
Recovery depends on the operation and on you. In general:
- First weeks: a protective post-operative shoe, keeping the foot elevated to control swelling, and keeping the dressing dry.
- Return to shoes and activity: gradual, over several weeks. Swelling can take a few months to settle fully.
- Numbness: expected in the adjoining sides of the two toes after neurectomy.
- Scar: may be tender for a while, especially on the sole.[6]
Risks
All surgery carries risk. Risks discussed before neuroma surgery include infection and wound-healing problems, a thickened or sensitive scar, blood clots, and persistent pain. After neurectomy, the cut nerve end can form a new painful neuroma, called a stump neuroma. When that happens, a second operation may move the nerve end to a place where it isn’t pressed on when you walk.[10,11] See revision nerve surgery.
Questions to ask before deciding
- How sure are we that a neuroma is causing my pain, and what else could it be?
- What non-surgical treatment have I tried, and is anything worth trying first?
- Which operation do you recommend for me, through which incision, and why?
- What numbness should I expect, and what is a realistic result?
- What will recovery mean for my shoes, work, driving and exercise?
When to seek care
Consider an evaluation if pain in the ball of your foot lasts more than a few weeks despite changing your shoes, or if pain has returned after neuroma surgery.
References
- 1.Cooper MT. Common Painful Foot and Ankle Conditions: A Review. JAMA. 2023;330(23):2285-2294. PubMed 38112812 (external site)
- 2.Choi JY, Hong WH, Kim MJ, Chae SW, Suh JS. Operative treatment options for Morton's neuroma other than neurectomy - a systematic review. Foot Ankle Surg. 2022;28(4):450-459. PubMed 34736848 (external site)
- 3.Lu VM, Puffer RC, Everson MC, Gilder HE, Burks SS, Spinner RJ. Treating Morton's neuroma by injection, neurolysis, or neurectomy: a systematic review and meta-analysis of pain and satisfaction outcomes. Acta Neurochir (Wien). 2021;163(2):531-543. PubMed 32056015 (external site)
- 4.Choi JY, Lee HI, Hong WH, Suh JS, Hur JW. Corticosteroid Injection for Morton's Interdigital Neuroma: A Systematic Review. Clin Orthop Surg. 2021;13(2):266-277. PubMed 34094019 (external site)
- 5.American Academy of Orthopaedic Surgeons. Morton’s Neuroma. OrthoInfo. orthoinfo.org (external site)
- 6.Lee W, McDonald J, Azam M, Lachance AD. The comparison of postoperative outcomes in Morton's neuroma excision between plantar versus dorsal approach: A systematic review and meta-analysis. Foot Ankle Surg. 2024;30(8):621-629. PubMed 38880729 (external site)
- 7.Habashy A, Sumarriva G, Treuting RJ. Neurectomy Outcomes in Patients With Morton Neuroma: Comparison of Plantar vs Dorsal Approaches. Ochsner J. 2016;16(4):471-474. PubMed 27999504 (external site)
- 8.Matthews BG, Thomson CE, Harding MP, McKinley JC, Ware RS. Treatments for Morton’s neuroma. Cochrane Database Syst Rev. 2024;2(2):CD014687. PubMed 38334217 (external site)
- 9.Elghazy MA, Whitelaw KC, Waryasz GR, Guss D, Johnson AH, DiGiovanni CW. Isolated Intermetatarsal Ligament Release as Primary Operative Management for Morton's Neuroma: Short-term Results. Foot Ankle Spec. 2022;15(4):338-345. PubMed 32954808 (external site)
- 10.Richardson DR, Dean EM. The recurrent Morton neuroma: what now? Foot Ankle Clin. 2014;19(3):437-449. PubMed 25129354 (external site)
- 11.Ettehadi H, Saragas NP, Ferrao P. Patient reported outcomes following revision neurectomy through a dorsal approach for recurrent interdigital neuroma. Foot Ankle Surg. 2022;28(8):1210-1214. PubMed 35393246 (external site)
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Related topics
Condition
Morton’s neuroma
Burning, sharp or numb sensations in the ball of the foot, often between the third and fourth toes.
Treatment
Neuroma treatment
Stepwise care for Morton’s neuroma and other painful neuromas, from footwear changes to surgery.
Treatment
Revision nerve surgery
A further operation for nerve symptoms that persist or return after previous neuroma or nerve-release surgery.
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